Editor-in-Chief: Alan David Kaye, MD, PhD
Managing Editor: Bert Fellows, MA

Pain Physician is the official publication of the American Society of Interventional Pain Physicians (ASIPP). The open access journal is published 6 times a year.

Pain Physician is a peer-reviewed, multi-disciplinary, open access journal written by and directed to an audience of interventional pain physicians, clinicians and basic scientists with an interest in interventional pain management and pain medicine.

Pain Physician presents the latest studies, research, and information vital to those in the emerging specialty of interventional pain management – and critical to the people they serve.


Epidural Guidelines Facet Joint Guidelines IPM Guidelines Regenerative Medicine Guidelines OPIOID Guidelines PNS Guidelines Risk Stratification Guideline Antithrombotic Guidelines Sedation Guidelines BMC Therapy Position Statement

Current issue highlights: (September 2025, Volume 28, Issue 5)

  1. Escalating Growth of Spending on Medicare Advantage Plans: Save Medicare from Insolvency and Balance the Budget
    Health Policy Perspective
    Laxmaiah Manchikanti, MD, Mahendra Sanapati, MD, Paul J. Hubbell, III, MD, Ann Conn, MD, Mayank Gupta, MD, Ramarao Pasupuleti, MD, Alaa Abd-Elsayed, MD, and Alan D. Kaye, MD, PhD.
  2. Physician Payment Reform in Interventional Pain Management: Balancing Cost, Quality, Access, and Survival of Independent Practices
    Health Policy Perspective
    Laxmaiah Manchikanti, MD, Mahendra Sanapati, MD, Vidyasagar Pampati, MSc, Paul J. Hubbell, III, MD, Ann Conn, MD, Ramarao Pasupuleti, MD, Mayank Gupta, MD, Alan D. Kaye, MD, PhD, Alaa Abd-Elsayed, MD, Annu Navani, MD, Miles Day, MD, Devi Nampiaparampil, MD, Christopher G. Gharibo, MD, and Joshua A. Hirsch, MD.
  3. The Past, Present, and Future of the Biopsychosocial Approach to Nonspecific Chronic Low Back Pain in Research and Clinical Practice Based on a Bibliometric Analysis
    Bibliometric Analysis
    Aybuke Fanuscu, PT, Iris Meuwissen, PT, and Mira Meeus, PT, PhD.
  4. BMJ Publications on Interventional Techniques Do Not Meet Appropriateness Criteria of Conducting a Rapid Review: A Comprehensive Review
    Health Policy Review
    Laxmaiah Manchikanti, MD, Mahendra Sanapati, MD, Amol Soin, MD, Alan D. Kaye, MD, PhD, Alaa Abd-Elsayed, MD, Christopher G. Gharibo, MD, Allen Dennis, MD, and Joshua A. Hirsch, MD.
  5. Effectiveness of Peripheral Nerve Stimulation in Managing Chronic Pain: A Systematic Review and Meta-analysis of Randomized Controlled Trials
    Systematic Review
    Laxmaiah Manchikanti, MD, Massab Bashir Khaira, MS, Amol Soin, MD, Alan D. Kaye, MD, PhD, Nebojsa Nick Knezevic, MD, PhD, Alaa Abd-Elsayed, MD, Mahendra Sanapati, MD, Vivekanand A. Manocha, MD, and Joshua A. Hirsch, MD.
  6. Optimizing Pain Relief in Refractory Thoracic Outlet Syndrome: The Role of Ultrasound-Guided Injections
    Literature Review
    Helen Gharaei, MD, and Negin Gholampoor, MBChB.
  7. A Prospective, Randomized, Controlled Clinical Trial of High-Frequency Electromagnetic Coupling Powered Permanent Peripheral Nerve Stimulator for the Treatment of Chronic Craniofacial Pain
    Randomized Controlled Trial
    Salim M. Hayek, MD, PhD, Nameer Haider, MD, Ashwin Viswanathan, MD, Mehul Desai, MD, Jeffrey Rosenberg, MD, and Niek E. Vanquathem, BS.
  8. Predictive Value of Preoperative Antioxidant Levels in Postherpetic Neuralgia: A Retrospective Study
    Retrospective Study
    JiaYu Yue, PhD, and Ming Yao, PhD.
  9. Nonlinear Association Between Serum Lutein and Zeaxanthin Levels and Low Back Pain in US Adults: Results from the National Health and Nutrition Examination Survey
    Cross-sectional Survey
    Shuai Qing, PhD, Shiming Huang, PhD, Jiang feng Wang, PhD, Min Xiao, PhD, and Qishan Yi, PhD.
  10. Full Endoscopic Decompression Surgery for Far-Out Syndrome Via Pseudoarthrosis Formed by L5 Transverse Process and Sacral Ala: A Preliminary Outcome
    Retrospective Analysis
    Hao Hu, MS, Fu-Kuan Zhu, MS, Lei Shi, MD, Rui Deng, MD, Xi-Zi Miao, MS, Ya-Feng Wen, MD, Zhen-Yong Ke, MD, Xiao-Min Sheng, MD, Lei Chu, MD, and Zhong-Liang Deng, MD, PhD.